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Merck's 1899 Manual of the Materia Medica is a comprehensive guide to the properties and uses of various drugs and chemicals available during the late 19th century. The book is written in a precise and scientific style, outlining the benefits and potential side effects of each substance. This manual serves as a valuable resource for scholars studying the medical practices of the time, offering an in-depth look at the pharmacological knowledge available in the late Victorian era.