The Domestic Church: Room by Room is so much more than a mother's study guide for women who want to deepen their understanding of their vocations. It is an exploration of Catholic teaching as it relates to our roles as women, wives, mothers, and citizens of the world at large. Referring back to Scripture, papal encyclicals, apostolic letters, the Catechism of the Catholic Church, and the words of the great saints, Donna weaves together the life story of every Catholic woman, regardless of her age, background, family situation, or career choice.

Through stories from her own life, including the personal friendship she shared with Blessed Mother Teresa of Calcutta, Donna demystifies the domestic church, offering concrete ways to find joy and spiritual fulfillment in the "nitty-gritty, humble work" of our daily lives.