Drawing on the concept of de/lirio—which articulates a series of disorders in the first-person literary enunciation, on the one hand, and the psychopathological characterization of this first person, on the other hand—the study explores the deviant lyric of Mario Levrero and Alberto Laiseca and shows how they respond productively to aesthetic, ethical and ontological problems of the turn of the millennium, in the Río de la Plata and beyond.